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GSAP Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-78400

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Simple Western, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

A synthetic peptide made to an internal portion of the human GSAP protein (between residues 150-200) [UniProt A4D1B5]

Localization

Golgi apparatus, trans-Golgi network.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GSAP Antibody - BSA Free

Western Blot: GSAP AntibodyBSA Free [NBP1-78400]

Western Blot: GSAP AntibodyBSA Free [NBP1-78400]

Western Blot: GSAP Antibody [NBP1-78400] - Analysis of GSAP in HepG2 cell lysate.
Simple Western: GSAP AntibodyBSA Free [NBP1-78400]

Simple Western: GSAP AntibodyBSA Free [NBP1-78400]

Simple Western: GSAP Antibody [NBP1-78400] - Simple Western lane view shows a specific band for GSAP in 0.5 mg/ml of HepG2 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

Applications for GSAP Antibody - BSA Free

Application
Recommended Usage

Simple Western

1:100

Western Blot

1:1000
Application Notes
This GSAP antibody is useful for Western Blot where a band is observed ~65 kDa representing Isoform 2/3 of GSAP.

In Simple Western only 10 - 15 uL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS and 30% Glycerol

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GSAP

Gamma secretase activating protein (GSAP) is implicated in Alzheimer's disease, through instigating plaque formation of amyloid beta. Immunohistochemistry to identify GSAP in brain can demonstrate its abundance in certain regions of damage, and is usually morphologically changed throughout the progression of Alzheimer's disease. GSAP can be used as a qualitative biomarker of Alzheimer's disease progression, and is regularly considered one of the best targets of therapies to diminish the effects of Alzheimer's disease in affected individuals.

Long Name

Gamma-Secretase Activating Protein

Alternate Names

PION, tcag7.1314, Gamma-secretase-activating protein

Entrez Gene IDs

54103 (Human)

Gene Symbol

GSAP

UniProt

Additional GSAP Products

Product Documents for GSAP Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GSAP Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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