GSTM2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-55103

Novus Biologicals, part of Bio-Techne
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NBP1-55103
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all GSTM2 Antibodies »

Product Summary for GSTM2 Antibody

Immunogen

Synthetic peptides corresponding to GSTM2(glutathione S-transferase M2 (muscle)) The peptide sequence was selected from the N terminal of GSTM2. Peptide sequence TQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

26 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for GSTM2 Antibody

Western Blot: GSTM2 Antibody [NBP1-55103]

Western Blot: GSTM2 Antibody [NBP1-55103]

Western Blot: GSTM2 Antibody [NBP1-55103] - Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0 ug/ml
Immunohistochemistry-Paraffin: GSTM2 Antibody [NBP1-55103]

Immunohistochemistry-Paraffin: GSTM2 Antibody [NBP1-55103]

Immunohistochemistry-Paraffin: GSTM2 Antibody [NBP1-55103] - Human Skeletal Muscle lysate tissue at an antibody concentration of 5.0ug/ml.
Western Blot: GSTM2 Antibody [NBP1-55103]

Western Blot: GSTM2 Antibody [NBP1-55103]

Western Blot: GSTM2 Antibody [NBP1-55103] - Reccomended Titration: 0.2 - 1 ug/ml Positive Control: Human Liver
View 1 more images

Applications for GSTM2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GSTM2

At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM2 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Alternate Names

glutathione S-transferase mu 2 (muscle), MGC117303, muscle, S-(hydroxyalkyl)glutathione lyase M2

Gene Symbol

GSTM2

UniProt

P28161 (Human)

Additional GSTM2 Products

Product Documents for GSTM2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GSTM2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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