Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all GTF2IRD1 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 650 and 700 of human general transcription factor 2I repeat domain containing 1 using the numbering given in entry NP_057412.1 (GeneID 9569).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GTF2IRD1 Antibody

Immunohistochemistry-Paraffin: GTF2IRD1 Antibody [NB100-61055]

Immunohistochemistry-Paraffin: GTF2IRD1 Antibody [NB100-61055]

Immunohistochemistry-Paraffin: GTF2IRD1 Antibody [NB100-61055] - Human prostate carcinoma. Antibody used at a dilution of 1:5,000.
Immunohistochemistry-Paraffin: GTF2IRD1 Antibody [NB100-61055]

Immunohistochemistry-Paraffin: GTF2IRD1 Antibody [NB100-61055]

Immunohistochemistry-Paraffin: GTF2IRD1 Antibody [NB100-61055] - FFPE section of human prostate carcinoma. Affinity purified rabbit anti-GTF2IRD/TFII-IRD1 used at a dilution of 1:500.
Immunoprecipitation: GTF2IRD1 Antibody [NB100-61055]

Immunoprecipitation: GTF2IRD1 Antibody [NB100-61055]

Immunoprecipitation: GTF2IRD1 Antibody [NB100-61055] - WB and Immunoprecipitation: GTF2IRD/TFII-IRD1 Antibody NB100-61055 - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. NB100-61055 used for IP at 3 ug/mg lysate. GTF2IRD1/TFII-IRD1 was also immunoprecipitated by rabbit anti-GTF2IRD1/TFII-IRD1 antibody NB100-60156, which recognizes a downstream epitope.

Applications for GTF2IRD1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000- 1:5000

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

2-5 ug/mg lysate
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: GTF2IRD1

The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants.

Alternate Names

BEN, CREAM1, General transcription factor III, general transcription factor II-I repeat domain-containing protein 1, GTF2I repeat domain containing 1, GTF2I repeat domain-containing protein 1, GTF3GTF2I repeat domain-containing 1, hMusTRD1alpha1, Muscle TFII-I repeat domain-containing protein 1, muscle TFII-I repeat domain-containing protein 1 alpha 1, MusTRD1, MusTRD1/BEN, MUSTRD1general transcription factor 3, RBAP2WBSCR12binding factor for early enhancer, Slow-muscle-fiber enhancer-binding protein, USE B1-binding protein, WBS, WBSCR11, Williams-Beuren syndrome chromosomal region 11 protein, Williams-Beuren syndrome chromosomal region 12 protein, Williams-Beuren syndrome chromosome region 11

Entrez Gene IDs

9569 (Human)

Gene Symbol

GTF2IRD1

UniProt

NP_057412.1 (Human)

Additional GTF2IRD1 Products

Product Documents for GTF2IRD1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GTF2IRD1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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