GTF3C2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83062

Novus Biologicals, part of Bio-Techne
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NBP1-83062
NBP1-83062-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GTF3C2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGFSPTSH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GTF3C2 Antibody

Western Blot: GTF3C2 Antibody [NBP1-83062]

Western Blot: GTF3C2 Antibody [NBP1-83062]

Western Blot: GTF3C2 Antibody [NBP1-83062] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp
Immunohistochemistry-Paraffin: GTF3C2 Antibody [NBP1-83062]

Immunohistochemistry-Paraffin: GTF3C2 Antibody [NBP1-83062]

Immunohistochemistry-Paraffin: GTF3C2 Antibody [NBP1-83062] - Staining of human duodenum shows strong positivity in smooth muscle cells.

Applications for GTF3C2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GTF3C2

General transcription factor 3C polypeptide 2 (GTF3C2/TFIIIC110) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. The functional contribution of GTF3C2/TFIIIC110 to the TFIIIC complex has not been fully determined. TFIIIC that is not associated with GTF3C2/TFIIIC110 has been purified, and it has been proposed that GTF3C2/TFIIIC110 functions to activate the TFIIIC complex for RNA polymerase III transcription. Recent studies argue against this model of GTF3C2/TFIIIC110 function.

Alternate Names

general transcription factor 3C polypeptide 2, general transcription factor IIIC, polypeptide 2, beta 110kDa, KIAA0011general transcription factor IIIC, polypeptide 2 (beta subunit, 110kD), TF3C-beta, TFIIIC 110 kDa subunit, TFIIIC110Transcription factor IIIC 110 kDa subunit, TFIIIC-BETA, Transcription factor IIIC subunit beta

Gene Symbol

GTF3C2

Additional GTF3C2 Products

Product Documents for GTF3C2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GTF3C2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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