gtf3c3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-60430

Novus Biologicals, part of Bio-Techne
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NB100-60430
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all gtf3c3 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 100 and 150 of human general transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) using the numbering given in entry NP_036218.1 (GeneID 9330).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for gtf3c3 Antibody

Immunoprecipitation: gtf3c3 Antibody [NB100-60430]

Immunoprecipitation: gtf3c3 Antibody [NB100-60430]

Immunoprecipitation: gtf3c3 Antibody [NB100-60430] - Detection of Human GTF3C3/TFIIIC102 on HeLa whole cell lysate using NB100-60430. GTF3C3/TFIIIC102 was also immunoprecipitated by rabbit anti-GTF3C3/TFIIIC102 antibody NB100-60431.

Applications for gtf3c3 Antibody

Application
Recommended Usage

Immunoprecipitation

1:10-1:500
Application Notes
This antibody is not recommended for Western Blot analysis.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: gtf3c3

General transcription factor 3C polypeptide 3 (GTF3C3/TFIIIC102) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C3/TFIIIC102 appears to be important for stable complex formation and recruitment of RNA polymerase III by interacting with TFIIIB90, TBP, and TFIIIC63. GTF3C3/TFIIIC102 has been shown to also interact with DEDD and FLAME-3 proteins. This interaction may function to translocate GTF3C3/TFIIIC102 to the nucleus and regulate TFIIIC activity. Alternate names for GTF3C3/TFIIIC102 include general transcription factor 3C polypeptide 3, transcription factor IIIC subunit gamma, TF3C-gamma, TFIIIC 102 kDa subunit, TFIIIC102, and general transcription factor IIIC polypeptide 3 (beta subunit, 102 kDa).

Alternate Names

general transcription factor 3C polypeptide 3, general transcription factor IIIC, polypeptide 3, 102kDa, TF3C-gamma, TFIIIC 102 kDa subunit, TFIIIC102general transcription factor IIIC, polypeptide 3 (102kD), TFiiiC2-102, TFIIICgamma, Transcription factor IIIC 102 kDa subunit, Transcription factor IIIC subunit gamma, transcription factor IIIC, 102 kD

Entrez Gene IDs

9330 (Human)

Gene Symbol

GTF3C3

UniProt

NP_036218.1 (Human)

Additional gtf3c3 Products

Product Documents for gtf3c3 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for gtf3c3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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