gtf3c3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56032

Novus Biologicals, part of Bio-Techne
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NBP2-56032
NBP2-56032-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (99%), Rat (99%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all gtf3c3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: RETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for gtf3c3 Antibody

Immunocytochemistry/ Immunofluorescence: gtf3c3 Antibody [NBP2-56032]

Immunocytochemistry/ Immunofluorescence: gtf3c3 Antibody [NBP2-56032]

Immunocytochemistry/Immunofluorescence: gtf3c3 Antibody [NBP2-56032] - Staining of human cell line U-2 OS shows localization to nucleoplasm & nuclear membrane. Antibody staining is shown in green.

Applications for gtf3c3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: gtf3c3

General transcription factor 3C polypeptide 3 (GTF3C3/TFIIIC102) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C3/TFIIIC102 appears to be important for stable complex formation and recruitment of RNA polymerase III by interacting with TFIIIB90, TBP, and TFIIIC63. GTF3C3/TFIIIC102 has been shown to also interact with DEDD and FLAME-3 proteins. This interaction may function to translocate GTF3C3/TFIIIC102 to the nucleus and regulate TFIIIC activity.

Alternate Names

general transcription factor 3C polypeptide 3, general transcription factor IIIC, polypeptide 3, 102kDa, TF3C-gamma, TFIIIC 102 kDa subunit, TFIIIC102general transcription factor IIIC, polypeptide 3 (102kD), TFiiiC2-102, TFIIICgamma, Transcription factor IIIC 102 kDa subunit, Transcription factor IIIC subunit gamma, transcription factor IIIC, 102 kD

Gene Symbol

GTF3C3

Additional gtf3c3 Products

Product Documents for gtf3c3 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for gtf3c3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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