Guanylyl Cyclase beta 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18694

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Porcine, Bovine

Applications

Dot Blot, ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Guanylyl Cyclase beta 1 Antibodies »

Product Summary for Guanylyl Cyclase beta 1 Antibody

Immunogen

Synthetic peptide taken within amino acid region 175-225 on rat guanylate cyclase soluble subunit beta-1 protein.

Localization

Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Description

0.75-1.2 ug/ul in antibody stabilization buffer

Heterodimer of an alpha and a beta chain. Homotetramer; dimer of dimers (in vitro).

Scientific Data Images for Guanylyl Cyclase beta 1 Antibody

Western Blot: Guanylyl Cyclase beta 1 Antibody [NBP3-18694]

Western Blot: Guanylyl Cyclase beta 1 Antibody [NBP3-18694]

Western Blot: Guanylyl Cyclase beta 1 Antibody [NBP3-18694] - Wesern blot of Guanylyl Cyclase beta 1 antibody (1:500) in DiluObuffer. Apparent MW is 76 kDa.
Immunohistochemistry: Guanylyl Cyclase beta 1 Antibody [NBP3-18694]

Immunohistochemistry: Guanylyl Cyclase beta 1 Antibody [NBP3-18694]

Immunohistochemistry: Guanylyl Cyclase beta 1 Antibody [NBP3-18694] - Rat cerebellum - soluble Guanylyl Cyclase beta 1 antibody (1:100) in IHC blocking buffer. DAB (brown) staining and hematoxylin QS (blue) counterstain. 40X magnification on Leica DM4000 microscope. FFPE section.
Immunohistochemistry: Guanylyl Cyclase beta 1 Antibody [NBP3-18694]

Immunohistochemistry: Guanylyl Cyclase beta 1 Antibody [NBP3-18694]

Immunohistochemistry: Guanylyl Cyclase beta 1 Antibody [NBP3-18694] - Rat cerebellum - soluble guanylate cyclase beta 1 primary antibody (1:100) in IHC blocking buffer. DAB (brown) staining and hematoxylin QS (blue) counterstain. 5X maginification on Leica DM4000 microscope. FFPE section.
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Applications for Guanylyl Cyclase beta 1 Antibody

Application
Recommended Usage

Dot Blot

1:10000

ELISA

1:10000

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Guanylyl Cyclase beta 1

Guanylate Cyclase is an heterodimer of an alpha and a beta chain. Its enzymatic activity transforms GTP to GMP releasing a diphosphate. It binds 1 or 2 hemes per heterodimer. It is activated by nitric oxide in the presence of magnesium or manganese ions. There are two types of guanylate cyclase: soluble form and membrane-associated receptor form.

Alternate Names

EC 4.6.1.2, GC-SB3, GCS-beta-1, GCS-beta-3, guanylate cyclase 1, soluble, beta 3, guanylate cyclase soluble subunit beta-1, Guanylate cyclase soluble subunit beta-3, GUC1B3GUCB3, GUCSB3GC-S-beta-1, GUCY1B1, Soluble guanylate cyclase small subunit

Gene Symbol

GUCY1B1

Additional Guanylyl Cyclase beta 1 Products

Product Documents for Guanylyl Cyclase beta 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Guanylyl Cyclase beta 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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