Haptoglobin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32391

Novus Biologicals, part of Bio-Techne
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NBP1-32391
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (98%), Rhesus Macaque (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Haptoglobin Antibodies »

Product Summary for Haptoglobin Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Haptoglobin. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (98%), Mouse (81%), Rat (80%), Cat (83%), Pig (81%), Rabbit (86%).

Localization

Secreted

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Haptoglobin Antibody

Western Blot: Haptoglobin Antibody [NBP1-32391]

Western Blot: Haptoglobin Antibody [NBP1-32391]

Western Blot: Haptoglobin Antibody [NBP1-32391] - Human plasma (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with Haptoglobin antibody diluted at 1:30000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunohistochemistry-Paraffin: Haptoglobin Antibody [NBP1-32391]

Immunohistochemistry-Paraffin: Haptoglobin Antibody [NBP1-32391]

Immunohistochemistry-Paraffin: Haptoglobin Antibody [NBP1-32391] - Paraffin-embedded Normal gastric, using antibody at 1:100 dilution.

Applications for Haptoglobin Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:5000-1:30000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 20% Glycerol (pH7)

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Haptoglobin

This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

HP, HP-1, hp2-alpha, HPA1S

Gene Symbol

HP

Additional Haptoglobin Products

Product Documents for Haptoglobin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Haptoglobin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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