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HDAC3 Antibody (RM439)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23463

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-23463

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM439

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for HDAC3 Antibody (RM439)

Immunogen

A peptide corresponding to the C-terminus of HDAC3 (Uniprot#: O15379)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HDAC3 Antibody (RM439)

HDAC3 Antibody (RM439)

Immunohistochemistry-Paraffin: HDAC3 Antibody (RM439) [NBP3-23463] -

Immunohistochemistry-Paraffin: HDAC3 Antibody (RM439) [NBP3-23463] - Immunohistochemical staining of formalin fixed and paraffin embedded human brain cancer tissue sections using Clone RM439) at 1:200 dilution.
HDAC3 Antibody (RM439)

Western Blot: HDAC3 Antibody (RM439) [NBP3-23463] -

Western Blot: HDAC3 Antibody (RM439) [NBP3-23463] - Western Blot of Jurkat cell lysate using Clone RM439) at 1:1000 dilution.
HDAC3 Antibody (RM439)

Immunohistochemistry-Paraffin: HDAC3 Antibody (RM439) [NBP3-23463] -

Immunohistochemistry-Paraffin: HDAC3 Antibody (RM439) [NBP3-23463] - Immunohistochemical staining of formalin fixed and paraffin embedded human lung squamous carcinoma tissue sections using Clone RM439) at 1:200 dilution.

Applications for HDAC3 Antibody (RM439)

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:200

Western Blot

1:1000 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Histone Deacetylase 3/HDAC3

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone cetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone acetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Long Name

Histone Deacetylase 3

Alternate Names

HDAC3, KDAC3, RPD3-2, SMAP45

Gene Symbol

HDAC3

Additional Histone Deacetylase 3/HDAC3 Products

Product Documents for HDAC3 Antibody (RM439)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HDAC3 Antibody (RM439)

[Public Notes]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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