Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation (Negative), Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all HDAC7 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 902 and 952 of human histone deacetylase 7A using the numbering given in entry NP_056216.1 (GeneID 51564).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HDAC7 Antibody

Western Blot: HDAC7 Antibody [NB100-61587]

Western Blot: HDAC7 Antibody [NB100-61587]

Western Blot: HDAC7 Antibody [NB100-61587] - Whole cell lysate (5, 15 and 50 ug) from HeLa cells. Antibody used for WB at 0.4 ug/ml.
Immunohistochemistry-Paraffin: HDAC7 Antibody [NB100-61587]

Immunohistochemistry-Paraffin: HDAC7 Antibody [NB100-61587]

Immunohistochemistry-Paraffin: HDAC7 Antibody [NB100-61587] - Human prostate carcinoma (left) and mouse colon carcinoma (right). Antibody used at a dilution of 1:5,000.

Applications for HDAC7 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:5000

Immunohistochemistry-Paraffin

1:1000 - 1:5000

Western Blot

1:2000-1:10000
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections. Immunoprecipitation Not recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: HDAC7

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via transcriptional corepressor SMRT. Multiple alternatively spliced transcript variants encoding several isoforms have been found for this gene.

Long Name

Histone deacetylase 7

Alternate Names

HD7, HD7a, HDAC7A

Entrez Gene IDs

51564 (Human)

Gene Symbol

HDAC7

UniProt

Q8WUI4 (Human)

Additional HDAC7 Products

Product Documents for HDAC7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HDAC7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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