HDAC7 [p Ser318] Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-03978

Novus Biologicals, part of Bio-Techne
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NBP2-03978
NBP2-03978SS
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Key Product Details

Species Reactivity

Validated:

Human, Bovine, Canine, Equine, Primate, Zebrafish

Predicted:

Chicken (90%), Mouse (90%), Rat (90%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all HDAC7 Antibodies »

Product Specifications

Immunogen

A synthetic peptide containing phospho-serine 318 of human HDAC7 was used as the immunogen.

Modification

p Ser318

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HDAC7 [p Ser318] Antibody - BSA Free

Western Blot: HDAC7 [p Ser318] AntibodyBSA Free [NBP2-03978]

Western Blot: HDAC7 [p Ser318] AntibodyBSA Free [NBP2-03978]

Western Blot: HDAC7 [p Ser318] Antibody [NBP2-03978] - Analysis of phospho HDAC7 in (A) recombinant fusion protein containing a phosphorylated serine at position 318 and (B) fusion protein containinug an unphosphorylated serine at position 318, using HDAC7 phospho antibody at 0.1 ug/mL.

Applications for HDAC7 [p Ser318] Antibody - BSA Free

Application
Recommended Usage

Western Blot

0.1 - 1 ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HDAC7

Histone deacetylase 7 is a thymus-specific, intracellular transcription factor belonging to the class IIa histone deacetylase family. Reports suggest that dephosphorylation and nuclear localization of HDAC-7 is promoted by Myosin phosphatase, thus regulating the repression of Nur77 and inhibition of apoptosis in CD4+CD8+ double-positive thymocytes. HDAC-7 plays a specific role in maintaining vascular integrity by repressing the expression of matrix metalloproteinase (MMP) 10. It promotes repression mediated by transcriptional corepressor NCOR2 and is an efficient corepressor of the androgen receptor (AR). It is also responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).

Long Name

Histone deacetylase 7

Alternate Names

HD7, HD7a, HDAC7A

Gene Symbol

HDAC7

UniProt

NP_055522 (Human)

Additional HDAC7 Products

Product Documents for HDAC7 [p Ser318] Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HDAC7 [p Ser318] Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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