Heparan Sulfate Proteoglycan 2 Antibody (A74) [Alexa Fluor® 405]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23523AF405

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Bovine

Applications

ELISA, Immunoaffinity Purification, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Alexa Fluor 405 (Excitation = 405 nm, Emission = 421 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # A74

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Heparan Sulfate Proteoglycan 2 Antibodies »

Product Summary for Heparan Sulfate Proteoglycan 2 Antibody (A74) [Alexa Fluor® 405]

Immunogen

Bovine corneal endothelial cells

Epitope

Epitope is located in domain V

Reactivity Notes

Bovine, Human

Specificity

Highly specific for perlecan. There is no evidence for cross-reactivity with other connective tissue proteins (vitronectin, fibronectin, elastin, collagen, laminin).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Heparan Sulfate Proteoglycan 2 Antibody (A74) [Alexa Fluor® 405]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunoaffinity Purification

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Heparan Sulfate Proteoglycan 2

Heparan sulfate proteoglycan is a major component of basement membranes, where the molecule may be involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. This form of HSPG, known as HSPG2 or perlecan, is encoded by a gene that maps to chromosome 1. The gene for the form of HSPG associated with the cell surface of fibroblasts has been mapped to human chromosome 8 (MIM 142460).[supplied by OMIM]

Alternate Names

basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1

Gene Symbol

HSPG2

Additional Heparan Sulfate Proteoglycan 2 Products

Product Documents for Heparan Sulfate Proteoglycan 2 Antibody (A74) [Alexa Fluor® 405]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Heparan Sulfate Proteoglycan 2 Antibody (A74) [Alexa Fluor® 405]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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