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Hepatitis C Virus Core Antigen Antibody (C7-50) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB120-2740

Novus Biologicals, part of Bio-Techne
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NB120-2740
NB120-2740-0.025mg

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Virus

Cited:

Human

Applications

Validated:

ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # C7-50

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Purified HCV core-GST fusion protein (genotype 1b).

Epitope

This antibody recognizes an epitope between amino acid residues 21-40 of HCV core protein. This sequence is conserved among different HCV strains.

Reactivity Notes

Human reactivity reported in literature (PMID: 16940534). Mouse reactivity reported in literature (PMID: 22984515).

Specificity

Detects hepatitis C virus (HCV) core protein from transfected human and primate cell lines.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Hepatitis C Virus Core Antigen Antibody (C7-50) - BSA Free

Application
Recommended Usage

ELISA

1:100 - 1:2000

Flow Cytometry

1:100

Immunofluorescence

1:10 - 1:500

Immunohistochemistry

1:10 - 1:500

Immunoprecipitation

1:10 - 1:500

Western Blot

1 ug/mL
Application Notes
IP usage was reported in scientific literature (PMID: 16940534). IHC usage reported in scientific literature (PMID: 15159022). WB: Detects a single ~21 kDa protein representing HCV core protein in various transfected cell lines. IF: Staining of HCV core protein in transfected chimp hepatocytes yields a staining pattern consistent with cytoplasmic and vesicular staining.

Reviewed Applications

Read 1 review rated 5 using NB120-2740 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Hepatitis C Virus Core Antigen

Hepatitis C virus (HCV) is the primary cause of non-A, non-B hepatitis and results in most HCV-infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. The 21 kDa core protein of HCV is well conserved among different HCV genotypes and may suppress hepatitis B virus replication in a phosphorylation dependent manner.

Alternate Names

Core protein p19, HCcAg, HCV core antigen, HCV core protein

Gene Symbol

POLY

Additional Hepatitis C Virus Core Antigen Products

Product Documents for Hepatitis C Virus Core Antigen Antibody (C7-50) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Hepatitis C Virus Core Antigen Antibody (C7-50) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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