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Hepatitis C Virus Core Antigen Antibody (C7-50) [PE/Cy7]

Novus Biologicals, part of Bio-Techne | Catalog # NB120-2740PECY7

Novus Biologicals, part of Bio-Techne
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NB120-2740PECY7
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Key Product Details

Species Reactivity

Human, Mouse, Virus

Applications

Flow Cytometry

Label

PE/Cy7 (Excitation = 488 nm, Emission = 778 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # C7-50

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Purified HCV core-GST fusion protein (genotype 1b).

Epitope

This antibody recognizes an epitope between amino acid residues 21-40 of HCV core protein. This sequence is conserved among different HCV strains.

Reactivity Notes

Human reactivity reported in literature (PMID: 16940534). Mouse reactivity reported in literature (PMID: 22984515).

Specificity

Detects hepatitis C virus (HCV) core protein from transfected human and primate cell lines.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Hepatitis C Virus Core Antigen Antibody (C7-50) [PE/Cy7]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Hepatitis C Virus Core Antigen

Hepatitis C virus (HCV) is the primary cause of non-A, non-B hepatitis and results in most HCV-infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. The 21 kDa core protein of HCV is well conserved among different HCV genotypes and may suppress hepatitis B virus replication in a phosphorylation dependent manner.

Alternate Names

Core protein p19, HCcAg, HCV core antigen, HCV core protein

Gene Symbol

POLY

Additional Hepatitis C Virus Core Antigen Products

Product Documents for Hepatitis C Virus Core Antigen Antibody (C7-50) [PE/Cy7]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Hepatitis C Virus Core Antigen Antibody (C7-50) [PE/Cy7]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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