HERC5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00051191-A01

Novus Biologicals, part of Bio-Techne
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H00051191-A01
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all HERC5 Antibodies »

Product Specifications

Immunogen

HERC5 (NP_057407, 915 a.a. - 1024 a.a.) partial recombinant protein with GST tag. YDWKTFEKNARYEPGYNSSHPTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNNMKITFCCPESWNERDPIRALTCFSVLFLPKYSTMETVEEALQEAINNNRGFG

Reactivity Notes

Other species not tested.

Specificity

HERC5 - hect domain and RLD 5

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for HERC5 Antibody

Western Blot: HERC5 Antibody [H00051191-A01]

Western Blot: HERC5 Antibody [H00051191-A01]

Western Blot: HERC5 Antibody [H00051191-A01] - Detection against Immunogen (38.21 KDa) .

Applications for HERC5 Antibody

Application
Recommended Usage

Western Blot

1:500
Application Notes
The quality control of this antibody is limited to Western blot on the immunizing protein. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

50% Glycerol

Preservative

No Preservative

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: HERC5

This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.

Alternate Names

CEB1E3 ISG15--protein ligase HERC5, CEBP1, cyclin-E binding protein 1, Cyclin-E-binding protein 1, EC 6.3.2, EC 6.3.2.-, HECT domain and RCC1-like domain-containing protein 5, hect domain and RLD 5, HECT E3 ubiquitin ligase, probable E3 ubiquitin-protein ligase HERC5

Entrez Gene IDs

51191 (Human)

Gene Symbol

HERC5

UniProt

NP_057407 (Human)

Additional HERC5 Products

Product Documents for HERC5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HERC5 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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