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Herpes Simplex Virus 1 Antibody (HSV1/4055R)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13913

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Virus

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # HSV1/4055R

Concentration

0.2 mg/ml

Product Specifications

Immunogen

Detergent-solubilized herpes simplex virus (HSV) type 1 infected cells

Reactivity Notes

HSV1 (Herpes Simplex Virus 1)

Localization

Cytoplasmic and/or Nuclear

Specificity

The antibody reacts with HSV type 1 specific antigen. It is suitable for detection of HSV in human cellular material obtained from superficial lesions or biopsies and for the early identification of HSV in infected tissue cultures. The herpes simplex virus (HSV) (also known as cold sore, night fever or fever blister) is a virus that causes a contagious disease. There are two main types of Herpes Simplex Virus (HSV), 1 and 2. The HSV-1 strain generally appears in the orofacial organs. HSV2 usually resides in the sacral ganglion at the base of the spine. All herpes viruses are morphologically identical: they have a large double-stranded DNA genome and the virion consists of an icosahedral nucleo-capsid, which is surrounded by a lipid bilayer envelope.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

200ug/ml of antibody purified by Protein A. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0 mg/ml. (NBP3-14103)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.

Scientific Data Images for Herpes Simplex Virus 1 Antibody (HSV1/4055R)

Immunohistochemistry-Paraffin: Herpes Simplex Virus 1 Antibody (HSV1/4055R) [NBP3-13913]

Immunohistochemistry-Paraffin: Herpes Simplex Virus 1 Antibody (HSV1/4055R) [NBP3-13913]

Immunohistochemistry-Paraffin: Herpes Simplex Virus 1 Antibody (HSV1/4055R) [NBP3-13913] - Formalin-fixed, paraffin-embedded human Esophageal Carcinoma stained with Herpes Simplex Virus 1 antibody (HSV1/4055R).

Applications for Herpes Simplex Virus 1 Antibody (HSV1/4055R)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Herpes Simplex Virus 1

Herpes simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell.

Alternate Names

Herpes simplex virus, Herpes simplex virus 1, Herpes simplex virus type 1, HSV 1, Human herpesvirus 1, Human herpesvirus type 1

Additional Herpes Simplex Virus 1 Products

Product Documents for Herpes Simplex Virus 1 Antibody (HSV1/4055R)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Herpes Simplex Virus 1 Antibody (HSV1/4055R)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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