HERPUD1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83268

Novus Biologicals, part of Bio-Techne
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NBP1-83268
NBP1-83268-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HERPUD1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LGPGFSGYTPYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HERPUD1 Antibody

Immunohistochemistry-Paraffin: HERPUD1 Antibody [NBP1-83268]

Immunohistochemistry-Paraffin: HERPUD1 Antibody [NBP1-83268]

Immunohistochemistry-Paraffin: HERPUD1 Antibody [NBP1-83268] - Staining of human testis shows strong cytoplasmic and nuclear positivity in cells in seminiferus ducts.

Applications for HERPUD1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HERPUD1

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined.

Alternate Names

HERPMIF1, homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-likedomain member 1 protein, homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-likedomain member 1, homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domainmember 1 protein, KIAA0025MMS-inducible, Methyl methanesulfonate (MMF)-inducible fragment protein 1, Mif1, SUP

Gene Symbol

HERPUD1

Additional HERPUD1 Products

Product Documents for HERPUD1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HERPUD1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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