Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24897

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein Heterogeneous Nuclear Ribonucleoprotein (A1-like) using the following amino acid sequence: GNFGGRSSGPYGGGGQYFAKPQNQGG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody

Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody Immunocytochemistry/Immunofluorescence: Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody [NBP3-24897]

Immunocytochemistry/Immunofluorescence: Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody [NBP3-24897]

Staining of human cell line Hep-G2 shows localization to nucleoplasm.

Applications for Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Heterogeneous Nuclear Ribonucleoprotein (A1-like)

The HNRNPA1 gene encodes a heterogeneous nuclear ribonucleoprotein A1-like (part of the hnRNPs) that functions in various processes such as the ordering of pre-mRNA into hnRNP particles, the transport of poly(A) mRNA to the cytoplams from the nucleus, as well as plays a part in the regulation of splice site selection. Additionally, HNRNPA1 also functions in HCV RNA replication. This gene functions in mRNA splicing and processing, coregulation of adrogen receptor activity, and in translational control. it has been known to interact with various genes such as DDV5, ILF3, DDX17, HNRNPC, and ABHD16A. HNRNPA1 has been researched in various diseases including: cystic fibrosis, colorectal cancer, crohn's disease, spinal cord disease, human t-cell leukemia virus type 1 and type 2, muscular atrophy, stomatitis, and metastasis efficiency.

Alternate Names

heterogeneous nuclear ribonucleoprotein A1-like 2, hnRNP A1-like 2, hnRNP core protein A1-like 2, HNRNPA1L, LOC144983, MGC102957

Gene Symbol

HNRNPA1L2

Additional Heterogeneous Nuclear Ribonucleoprotein (A1-like) Products

Product Documents for Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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