HEXO Antibody (OTI1B3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-01655

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Rat, Monkey, Primate

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # OTI1B3

Concentration

1.1 mg/ml

View all HEXO Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human ERI1(NP_699163) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

39.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for HEXO Antibody (OTI1B3)

Western Blot: HEXO Antibody (OTI1B3) [NBP2-01655]

Western Blot: HEXO Antibody (OTI1B3) [NBP2-01655]

Western Blot: HEXO Antibody (OTI1B3) [NBP2-01655] - Analysis of extracts (35ug) from 9 different cell lines by using anti-HEXO monoclonal antibody.
Immunohistochemistry-Paraffin: HEXO Antibody (OTI1B3) [NBP2-01655]

Immunohistochemistry-Paraffin: HEXO Antibody (OTI1B3) [NBP2-01655]

Immunohistochemistry-Paraffin: HEXO Antibody (OTI1B3) [NBP2-01655] - Staining of paraffin-embedded Human tonsil using anti-HEXO mouse monoclonal antibody.
Western Blot: HEXO Antibody (OTI1B3) [NBP2-01655]

Western Blot: HEXO Antibody (OTI1B3) [NBP2-01655]

Western Blot: HEXO Antibody (OTI1B3) [NBP2-01655] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HEXO (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HEXO.
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Applications for HEXO Antibody (OTI1B3)

Application
Recommended Usage

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:500-2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: HEXO

HEXO is a 50-kD protein containing a SAP domain capable of recognizing AT-rich scaffold-attachment regions (SARs) in chromosomal DNA, and a exonuclease domain similar to those of DEDD exonuclease family members. HEXO is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as a regulator of RNA interference (RNAi).

Alternate Names

3' exoribonuclease, 3'-5' exonuclease ERI1, 3'EXO, 3'HEXO, EC 3.1, enhanced RNAi three prime mRNA exonuclease homolog 1, Eri-1 homolog, exoribonuclease 1, HEXO, histone mRNA 3' end-specific exonuclease, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-exonuclease 1, MGC35395, Protein 3'hExo, THEX1, three prime histone mRNA exonuclease 1,3'-5' exoribonuclease 1, three prime mRNA exonuclease 1

Entrez Gene IDs

90459 (Human)

Gene Symbol

ERI1

Additional HEXO Products

Product Documents for HEXO Antibody (OTI1B3)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for HEXO Antibody (OTI1B3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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