HEXO Antibody (OTI1B3) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-72312

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Rat, Monkey, Primate

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # OTI1B3

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all HEXO Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human ERI1(NP_699163) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

39.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for HEXO Antibody (OTI1B3) - Azide and BSA Free

Western Blot: HEXO Antibody (OTI1B3)Azide and BSA Free [NBP2-72312]

Western Blot: HEXO Antibody (OTI1B3)Azide and BSA Free [NBP2-72312]

Western Blot: HEXO Antibody (OTI1B3) - Azide and BSA Free [NBP2-72312] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HEXO (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HEXO.
Immunohistochemistry: HEXO Antibody (OTI1B3) - Azide and BSA Free [NBP2-72312]

Immunohistochemistry: HEXO Antibody (OTI1B3) - Azide and BSA Free [NBP2-72312]

Immunohistochemistry: HEXO Antibody (OTI1B3) - Azide and BSA Free [NBP2-72312] - Staining of paraffin-embedded Human Kidney tissue using anti-HEXO mouse monoclonal antibody.
Flow Cytometry: HEXO Antibody (OTI1B3) - Azide and BSA Free [NBP2-72312]

Flow Cytometry: HEXO Antibody (OTI1B3) - Azide and BSA Free [NBP2-72312]

Flow Cytometry: HEXO Antibody (OTI1B3) - Azide and BSA Free [NBP2-72312] - Analysis of extracts (35ug) from 9 different cell lines by using anti-HEXO monoclonal antibody.
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Applications for HEXO Antibody (OTI1B3) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:150

Western Blot

1:500-2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Reconstitution

we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process.

Formulation

Lyophilized from PBS (pH 7.3) with 8% Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: HEXO

HEXO is a 50-kD protein containing a SAP domain capable of recognizing AT-rich scaffold-attachment regions (SARs) in chromosomal DNA, and a exonuclease domain similar to those of DEDD exonuclease family members. HEXO is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as a regulator of RNA interference (RNAi).

Alternate Names

3' exoribonuclease, 3'-5' exonuclease ERI1, 3'EXO, 3'HEXO, EC 3.1, enhanced RNAi three prime mRNA exonuclease homolog 1, Eri-1 homolog, exoribonuclease 1, HEXO, histone mRNA 3' end-specific exonuclease, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-exonuclease 1, MGC35395, Protein 3'hExo, THEX1, three prime histone mRNA exonuclease 1,3'-5' exoribonuclease 1, three prime mRNA exonuclease 1

Gene Symbol

ERI1

Additional HEXO Products

Product Documents for HEXO Antibody (OTI1B3) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for HEXO Antibody (OTI1B3) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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