Hexosaminidase A/HEXA Antibody (3D1)

Novus Biologicals, part of Bio-Techne | Catalog # H00003073-M06

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 3D1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Hexosaminidase A/HEXA Antibodies »

Product Specifications

Immunogen

HEXA (AAH18927, 1 a.a. ~ 529 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MTSSRLWFSLLLAAAFAGRATALWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELLRRGVQAQPLNVGFCEQEFEQT

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Hexosaminidase A/HEXA Antibody (3D1)

Western Blot: Hexosaminidase A/HEXA Antibody (3D1) [H00003073-M06]

Western Blot: Hexosaminidase A/HEXA Antibody (3D1) [H00003073-M06]

Western Blot: Hexosaminidase A/HEXA Antibody (3D1) [H00003073-M06] - Analysis of HEXA expression in transfected 293T cell line by HEXA monoclonal antibody (M06), clone 3D1. Lane 1: HEXA transfected lysatE (60.7 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: Hexosaminidase A/HEXA Antibody (3D1) [H00003073-M06]

Immunocytochemistry/ Immunofluorescence: Hexosaminidase A/HEXA Antibody (3D1) [H00003073-M06]

Immunocytochemistry/Immunofluorescence: Hexosaminidase A/HEXA Antibody (3D1) [H00003073-M06] - Analysis of monoclonal antibody to HEXA on HeLa cell. Antibody concentration 10 ug/ml
Western Blot: Hexosaminidase A/HEXA Antibody (3D1) [H00003073-M06]

Western Blot: Hexosaminidase A/HEXA Antibody (3D1) [H00003073-M06]

Western Blot: Hexosaminidase A/HEXA Antibody (3D1) [H00003073-M06] - Analysis of HEXA expression in HeLa.
View 1 more images

Applications for Hexosaminidase A/HEXA Antibody (3D1)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
It has been used for ELISA and WB.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Hexosaminidase A/HEXA

HEXA encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq]

Alternate Names

HEXA, TSD

Gene Symbol

HEXA

UniProt

AAH18927 (Human)

Additional Hexosaminidase A/HEXA Products

Product Documents for Hexosaminidase A/HEXA Antibody (3D1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Hexosaminidase A/HEXA Antibody (3D1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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