HFE Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59055

Novus Biologicals, part of Bio-Techne
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NBP1-59055
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

0.5 mg/ml

View all HFE Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to HFE(hemochromatosis) The peptide sequence was selected from the C terminal of HFE. Peptide sequence FEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for HFE Antibody - BSA Free

Western Blot: HFE Antibody [NBP1-59055]

Western Blot: HFE Antibody [NBP1-59055]

Western Blot: HFE Antibody [NBP1-59055] - HepG2 cell lysate, Antibody Titration: 0.2-1 ug/ml
Immunohistochemistry-Paraffin: HFE Antibody [NBP1-59055]

Immunohistochemistry-Paraffin: HFE Antibody [NBP1-59055]

Immunohistochemistry-Paraffin: HFE Antibody [NBP1-59055] - Human kidney Tissue, antibody concentration 4-8ug/ml. Cells with positive label: renal corpuscle cells (indicated with arrows) 400X magnification.

Applications for HFE Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HFE

HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least eleven alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Long Name

Homeostatic Iron Regulator

Alternate Names

HFE1, HLA-H, MVCD7, TFQTL2

Gene Symbol

HFE

UniProt

Q30201-4 (Human)

Additional HFE Products

Product Documents for HFE Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for HFE Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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