Histamine H2R Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-78790

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Mouse, Rat

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Histamine H2 R Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-SHNSHKTSLRLNNS, from the internal region of the protein sequence according to NP_001399939.1; NP_001010973.1.

Specificity

This antibody is expected to recognize Mouse NP_001399939.1 iso 3, NP_001010973.1 iso 1 and Rat NP_001010973.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Histamine H2R Antibody

Histamine H2R Antibody

Western Blot: Histamine H2R Antibody [NBP1-78790] -

Western Blot: Histamine H2R Antibody [NBP1-78790] - (0.5ug/ml) staining of Mouse Stomach lysate (A) and (2ug/ml) Rat Small Intestine lysate (B) (35ug protein in RIPA buffer). Detected by chemiluminescence.

Applications for Histamine H2R Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

0.5-2 ug/ml
Application Notes
WB: Approx. 50kDa band observed in Mouse Stomach and Rat Small Intestine lysates (calculated MW of 47.3kDa according to Mouse NP_001399939.1 and 45.2kDa according to Rat NP_001399940.1). Primary incubation 1 hour at room temperature.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Histamine H2 R

HRH2 encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

Long Name

Histamine H2 Receptor

Alternate Names

Gastric Receptor 1, Histamine H2R, HRH2

Entrez Gene IDs

3274 (Human)

Gene Symbol

HRH2

UniProt

NP_001124527.1 (Human)

Additional Histamine H2 R Products

Product Documents for Histamine H2R Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Histamine H2R Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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