Histone H1.1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12893

Novus Biologicals, part of Bio-Techne
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NBP3-12893
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Histone H1.1 Antibodies »

Product Summary for Histone H1.1 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Histone H1.1. The exact sequence is proprietary.

Reactivity Notes

Rhesus Monkey (86%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for Histone H1.1 Antibody

Western Blot: Histone H1.1 Antibody [NBP3-12893]

Western Blot: Histone H1.1 Antibody [NBP3-12893]

Western Blot: Histone H1.1 Antibody [NBP3-12893] - HeLa whole cell and nuclear extracts (30 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with Histone H1.1 antibody (NBP3-12893) diluted at 1:1000.

Applications for Histone H1.1 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Histone H1.1

Histones are nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber as they play a critical role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Histone H1.1 is a 215 amino acid long, 21 kDA protein encoded by the HIST1H1A gene. H1 proteins are essential in forming chromatin fiber and for the condensation of nucleosome chains into higher-order structured fibers. The HIST1H1A gene is active in apoptosis, PKA signaling, histone modification, and granzyme-A pathways. It interacts with genes CDK2, CDK7, CTCFL, DOT1L, and ADPRH. The HIST1H1A gene has been researched regarding measles, breast cancer, prostatitis, carcinoma, paratyphoid fever, and neuronitis.

Alternate Names

H1 histone family, member 1, H1.1, H1A, H1F1HIST1, histone 1, H1a, histone cluster 1, H1a, histone H1.1, MGC126642, MGC138345

Gene Symbol

H1-1

Additional Histone H1.1 Products

Product Documents for Histone H1.1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Histone H1.1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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