Histone H2AX Antibody [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # NB100-638F

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NB100-638

Alexa Fluor 350

NB100-638AF350

Alexa Fluor 405

NB100-638AF405

Alexa Fluor 488

NB100-638AF488

Alexa Fluor 532

NB100-638AF532

Alexa Fluor 594

NB100-638AF594

Alexa Fluor 647

NB100-638AF647

Alexa Fluor 700

NB100-638AF700

Alexa Fluor 750

NB100-638AF750

Biotin

NB100-638B

CoraFluor 1

NB100-638CL1

DyLight 350

NB100-638UV

DyLight 405

NB100-638V

DyLight 488

NB100-638G

DyLight 550

NB100-638R

DyLight 594

NB100-638DL594

DyLight 650

NB100-638C

DyLight 680

NB100-638FR

DyLight 755

NB100-638IR

HRP

NB100-638H

Janelia Fluor 525

NB100-638JF525

Janelia Fluor 549

NB100-638JF549

Janelia Fluor 646

NB100-638JF646

Janelia Fluor 669

NB100-638JF669

PE

NB100-638PE

PerCP

NB100-638PCP

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot, Western Blot (Negative)

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Histone H2AX Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to the C-terminus of human histone H2AX using the numbering given for Swiss-Prot entry P16104 (GeneID 3014).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for Histone H2AX Antibody [FITC]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Western Blot (Negative)

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Histone H2AX

Histone H2AX is one of a number of core histone proteins. In the cellular response to genotoxic insults, ATM and related protein kinases phosphorylate the carboxyl-terminal tail of the H2AX protein (gamma-H2AX). gamma-H2AX marks the site of damage and provides a nucleation site for the formation of damage response and repair complexes. BRCA1 carboxyl terminal (BRCT) domain-containing proteins are recruited to gamma-H2AX to create a protein scaffold for further assembly of signaling complexes.

Alternate Names

H2AFX

Entrez Gene IDs

3014 (Human); 15270 (Mouse)

Gene Symbol

H2AX

Additional Histone H2AX Products

Product Documents for Histone H2AX Antibody [FITC]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Histone H2AX Antibody [FITC]

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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