Histone H3.1 [Methyl Lys79] Antibody (2G10)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26136

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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NBP3-26136-100ul
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Key Product Details

Species Reactivity

Human, Rat

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 2G10

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Histone H3.1 Antibodies »

Product Specifications

Immunogen

Synthesized peptide. The Histone H3.1 [Methyl Lys79] Recombinant Monoclonal Antibody was raised against a mixture of peptides containing 1, 2 or 3 methyl groups, such as DF-(Me1)K-TD & DF-(Me2)K-TD & DF-(Me3)K-TD. [UniProt P68431]

Modification

Methyl Lys 79

Specificity

May recognize any number of the three methyl groups on K79

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for Histone H3.1 [Methyl Lys79] Antibody (2G10)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl and 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: Histone H3.1

In eukaryotes, DNA is wrapped around histone octamers to form the basic unit of chromatin structure. The octamer is composed of Histones H2A, H2B, H3 and H4, and it associates with approximately 200 base pairs of DNA to form the nucleosome. The association of DNA with histones results in dense packing of chromatin, which restricts proteins involved in gene transcription from binding to DNA. Histone H3, the core protein of the nucleosome, becomes phosphorylated at the end of prophase. The two major sites of phosphorylation are the mitosis-specific site Ser 10 and Ser 28, both of which are extensively phosphorylated in DNA-bound forms of Histone H3 and in nucleosomal Histone H3. The nucleosome structure of Histone H3 promotes N-terminal phosphorylation in vitro. Phosphorylation of Histone H3 at Ser 10 is an essenti

Long Name

Histone Cluster 1 H3 Family Member A

Alternate Names

HIST1H3A

Gene Symbol

HIST1H3E

Additional Histone H3.1 Products

Product Documents for Histone H3.1 [Methyl Lys79] Antibody (2G10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Histone H3.1 [Methyl Lys79] Antibody (2G10)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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