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HIV-1 gp120 Antibody (4F4E4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-06629

Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-06629-100ul
NBP3-06629-50ul

Key Product Details

Species Reactivity

Validated:

Virus

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 4F4E4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for HIV-1 gp120 Antibody (4F4E4)

Immunogen

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant HIV-1 gp120 (Ala29-Glu502; Accession#: AFM77980.1).

Reactivity Notes

Human Immunodeficiency Virus type 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Applications for HIV-1 gp120 Antibody (4F4E4)

Application
Recommended Usage

ELISA

1:1000-1:2000

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HIV-1 gp120

HIV-1 gp120 is a surface glycoprotein that enables viral attachment and entry into host cells. It is also involved in neurotoxicity and has been implicated in HIV-associated neurocognitive disorders. HIV-1 gp120 also induces apoptosis in neuronal cells by signaling mitochondrial-death proteins which may upregulate the death receptor, Fas. Because HIV gp120 is necessary for HIV-1 to enter CD4 cells, gp120 is one of the main targets of HIV vaccine research.

Alternate Names

Envelope surface glycoprotein gp120, gp120, gp120 glycoprotein, Human immunodeficiency virus 1, SU, Surface protein

Gene Symbol

env

Additional HIV-1 gp120 Products

Product Documents for HIV-1 gp120 Antibody (4F4E4)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HIV-1 gp120 Antibody (4F4E4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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