HIV-1 gp120 Antibody (4F4E4) [Janelia Fluor® 525]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-06629JF525

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Virus

Applications

ELISA, Western Blot

Label

Janelia Fluor 525

Antibody Source

Monoclonal Mouse IgG2B Clone # 4F4E4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all HIV-1 gp120 Antibodies »

Product Summary for HIV-1 gp120 Antibody (4F4E4) [Janelia Fluor® 525]

Immunogen

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant HIV-1 gp120 (Ala29-Glu502; Accession#: AFM77980.1).

Reactivity Notes

Human Immunodeficiency Virus type 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for HIV-1 gp120 Antibody (4F4E4) [Janelia Fluor® 525]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: HIV-1 gp120

HIV-1 gp120 is a surface glycoprotein that enables viral attachment and entry into host cells. It is also involved in neurotoxicity and has been implicated in HIV-associated neurocognitive disorders. HIV-1 gp120 also induces apoptosis in neuronal cells by signaling mitochondrial-death proteins which may upregulate the death receptor, Fas. Because HIV gp120 is necessary for HIV-1 to enter CD4 cells, gp120 is one of the main targets of HIV vaccine research.

Alternate Names

Envelope surface glycoprotein gp120, gp120, gp120 glycoprotein, Human immunodeficiency virus 1, SU, Surface protein

Gene Symbol

env

Additional HIV-1 gp120 Products

Product Documents for HIV-1 gp120 Antibody (4F4E4) [Janelia Fluor® 525]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HIV-1 gp120 Antibody (4F4E4) [Janelia Fluor® 525]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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