HIV-1 gp120 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76371

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Virus

Cited:

Human

Applications

Validated:

ELISA, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all HIV-1 gp120 Antibodies »

Product Specifications

Immunogen

Antibody was raised against 16 amino acid synthetic peptide representing the major HIV-1 consensus sequence near the N-terminal region of V1/V2 loop. The immunogen is located within amino acids 80 - 130 of gp120. Amino Acid Squence: EQMHEDIISLWDQLSK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

120 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for HIV-1 gp120 Antibody - BSA Free

Western Blot: HIV-1 gp120 AntibodyBSA Free [NBP1-76371]

Western Blot: HIV-1 gp120 AntibodyBSA Free [NBP1-76371]

Western Blot: HIV-1 gp120 Antibody [NBP1-76371] - Analysis of 5 ng of gp120 with gp120 antibody at 1 ug/mL.

Applications for HIV-1 gp120 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HIV-1 gp120

Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

Alternate Names

Envelope surface glycoprotein gp120, gp120, gp120 glycoprotein, Human immunodeficiency virus 1, SU, Surface protein

Gene Symbol

env

UniProt

Q6BBS3 (Virus)

Additional HIV-1 gp120 Products

Product Documents for HIV-1 gp120 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HIV-1 gp120 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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