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HLA Class I Antibody (MEM-123) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NB500-505PE

Novus Biologicals, part of Bio-Techne
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NB500-505PE

Key Product Details

Species Reactivity

Human, Bovine, Primate

Applications

CyTOF-ready, ELISA, Flow Cytometry, Immunoprecipitation

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Mouse IgG3 Clone # MEM-123

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

COS-7 African green monkey kidney cells

Specificity

This antibody (clone MEM-123) reacts with all human classical MHC Class I molecules (major histocompatibility complex) in native cell-surface forms as well as with human HLA-G cDNA transfected cells. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. This antibody completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-blocks This antibody MEM-G/9.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3

Applications for HLA Class I Antibody (MEM-123) [PE]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: HLA Class I

HLA CLass I is involved in the presentation of foreign antigens to the immune system. This antibody is a valuable reagent for analysing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders. This antibody is also suitable as a positive control for HLA tissue typing and crossmatching.

Long Name

Class I Human Leukocyte Antigen

Alternate Names

HLA-A, HLA-ABC

Entrez Gene IDs

3107 (Human); 3106 (Human)

Gene Symbol

HLA-C

Additional HLA Class I Products

Product Documents for HLA Class I Antibody (MEM-123) [PE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HLA Class I Antibody (MEM-123) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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