hnRNP-Q Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34068

Novus Biologicals, part of Bio-Techne
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NBP2-34068
NBP2-34068-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all hnRNP-Q Antibodies »

Product Summary for hnRNP-Q Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: GNGTEEPMDTTSAVIHSENFQTLLDAG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for hnRNP-Q Antibody

Western Blot: hnRNP-Q Antibody [NBP2-34068]

Western Blot: hnRNP-Q Antibody [NBP2-34068]

Western Blot: hnRNP-Q Antibody [NBP2-34068] - Analysis in human cell line Daudi.
Immunocytochemistry/ Immunofluorescence: hnRNP-Q Antibody [NBP2-34068]

Immunocytochemistry/ Immunofluorescence: hnRNP-Q Antibody [NBP2-34068]

Immunocytochemistry/Immunofluorescence: hnRNP-Q Antibody [NBP2-34068] - Staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: hnRNP-Q Antibody [NBP2-34068]

Immunohistochemistry-Paraffin: hnRNP-Q Antibody [NBP2-34068]

Immunohistochemistry-Paraffin: hnRNP-Q Antibody [NBP2-34068] - Staining in human thyroid gland and pancreas tissues using anti-SYNCRIP antibody. Corresponding SYNCRIP RNA-seq data are presented for the same tissues.
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Applications for hnRNP-Q Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: hnRNP-Q

Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins

Alternate Names

dJ3J17.2, Glycine- and tyrosine-rich RNA-binding protein, GRYRBP, GRY-RBPNS1-associated protein 1, heterogeneous nuclear ribonucleoprotein Q, hnRNP Q, hnRNP-Q, HNRPQ, HNRPQ1, NSAP1FLJ31626, PP68, synaptotagmin binding, cytoplasmic RNA interacting protein, Synaptotagmin-binding, cytoplasmic RNA-interacting protein

Gene Symbol

SYNCRIP

UniProt

O60506 (Human)

Additional hnRNP-Q Products

Product Documents for hnRNP-Q Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for hnRNP-Q Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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