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HNRPGT Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13211

Novus Biologicals, part of Bio-Techne
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NBP2-13211
NBP2-13211-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TPPSYGGGGRYEEYRGYSPDAYS

Reactivity Notes

Reactivity reported in scientific literature (PMID: 24309898)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HNRPGT Antibody

Immunohistochemistry-Paraffin: HNRPGT Antibody [NBP2-13211]

Immunohistochemistry-Paraffin: HNRPGT Antibody [NBP2-13211]

Immunohistochemistry-Paraffin: HNRPGT Antibody [NBP2-13211] Staining of human testis shows strong nuclear positivity in cells in seminiferus ducts.

Applications for HNRPGT Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HNRPGT

HNRNPG belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.

Alternate Names

hnRNP G-T, HNRNPG-T, HNRNPGTRNA-binding motif protein, X-linked-like-2, HNRPGTheterogeneous nuclear ribonucleoprotein G T, RNA binding motif protein, X-linked-like 2, testes specific heterogenous nuclear ribonucleoprotein G T, testes-specific heterogenous nuclear ribonucleoprotein G-T, Testis-specific heterogeneous nuclear ribonucleoprotein G-T

Gene Symbol

RBMXL2

Additional HNRPGT Products

Product Documents for HNRPGT Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HNRPGT Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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