HO-1/HMOX1/HSP32 Antibody (CL11669) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44184

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL11669

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all HO-1/HMOX1/HSP32 Antibodies »

Product Specifications

Immunogen

This antibody was generated using a recombinant protein sequence of P09601, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for HO-1/HMOX1/HSP32 Antibody (CL11669) - Azide and BSA Free

HO-1/HMOX1/HSP32 Antibody (CL11669) - Azide and BSA Free Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody [NBP3-44184]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody [NBP3-44184]

Analysis in human spleen and skeletal muscle tissues using NBP3-44184 antibody. Corresponding HO-1/HMOX1/HSP32 RNA-seq data are presented for the same tissues.
HO-1/HMOX1/HSP32 Antibody (CL11669) - Azide and BSA Free Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody [NBP3-44184]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody [NBP3-44184]

Staining of human fallopian tube shows no positivity in glandular cells as expected.
HO-1/HMOX1/HSP32 Antibody (CL11669) - Azide and BSA Free Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody [NBP3-44184]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody [NBP3-44184]

Staining of human prostate shows no positivity in glandular cells as expected.
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Applications for HO-1/HMOX1/HSP32 Antibody (CL11669) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:200 -1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HO-1/HMOX1/HSP32

Stressed mammalian cells up-regulate heme oxygenase 1 (HO-1), which catabolizes heme to biliverdin, carbon monoxide, and free iron. Results provide genetic evidence that up-regulation of HO-1 serves as an adaptive mechanism to protect cells from oxidative damage during stress (1). When cells are injured they release their contents, resulting in a local accumulation of free heme proteins and heme. HO-1 plays a crucial role in the inflammatory process during wound healing (2). TNFalpha accelerates inflammatory responses by down-regulating HO-1 expression in human monocytes. TNF antagonists may block this TNF-dependent suppression of HO-1 expression, resulting in an amelioration of inflammation (3).

Long Name

Heme Oxygenase 1

Alternate Names

HMOX1, HO1, HSP32

Gene Symbol

HMOX1

Additional HO-1/HMOX1/HSP32 Products

Product Documents for HO-1/HMOX1/HSP32 Antibody (CL11669) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HO-1/HMOX1/HSP32 Antibody (CL11669) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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