HO-1/HMOX1/HSP32 Antibody (SP08-07)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-67382

Recombinant Monoclonal Antibody.
Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-67382
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse

Applications

Flow Cytometry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SP08-07

Concentration

1 mg/ml

View all HO-1/HMOX1/HSP32 Antibodies »

Product Specifications

Immunogen

Synthetic peptide within Human HO-1/HMOX1/HSP32 aa 227-276 / 288. (SwissProt: P09601 Human)

Localization

Microsome, Endoplasmic reticulum membrane.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HO-1/HMOX1/HSP32 Antibody (SP08-07)

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (SP08-07) [NBP2-67382]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (SP08-07) [NBP2-67382]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (SP08-07) [NBP2-67382] - Analysis of paraffin-embedded mouse liver tissue using anti-HO-1 antibody. Counter stained with hematoxylin.
Flow Cytometry: HO-1/HMOX1/HSP32 Antibody (SP08-07) [NBP2-67382]

Flow Cytometry: HO-1/HMOX1/HSP32 Antibody (SP08-07) [NBP2-67382]

Flow Cytometry: HO-1/HMOX1/HSP32 Antibody (SP08-07) [NBP2-67382] - Analysis of Jurkat cells with HO-1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as secondary antibody.
Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (SP08-07) [NBP2-67382]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (SP08-07) [NBP2-67382]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (SP08-07) [NBP2-67382] - Analysis of paraffin-embedded human liver tissue using anti-HO-1 antibody. Counter stained with hematoxylin.
View 1 more images

Applications for HO-1/HMOX1/HSP32 Antibody (SP08-07)

Application
Recommended Usage

Flow Cytometry

1:50-1:100

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

TBS (pH7.4), 0.05% BSA, 40% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HO-1/HMOX1/HSP32

Stressed mammalian cells up-regulate heme oxygenase 1 (HO-1), which catabolizes heme to biliverdin, carbon monoxide, and free iron. Results provide genetic evidence that up-regulation of HO-1 serves as an adaptive mechanism to protect cells from oxidative damage during stress (1). When cells are injured they release their contents, resulting in a local accumulation of free heme proteins and heme. HO-1 plays a crucial role in the inflammatory process during wound healing (2). TNFalpha accelerates inflammatory responses by down-regulating HO-1 expression in human monocytes. TNF antagonists may block this TNF-dependent suppression of HO-1 expression, resulting in an amelioration of inflammation (3).

Long Name

Heme Oxygenase 1

Alternate Names

HMOX1, HO1, HSP32

Gene Symbol

HMOX1

Additional HO-1/HMOX1/HSP32 Products

Product Documents for HO-1/HMOX1/HSP32 Antibody (SP08-07)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HO-1/HMOX1/HSP32 Antibody (SP08-07)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.