HOMER1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-44999

Novus Biologicals, part of Bio-Techne
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NBP1-44999
NBP1-44999SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Predicted:

Bovine (98%), Rat (99%), Xenopus (96%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all HOMER1 Antibodies »

Product Specifications

Immunogen

N-terminal partial recombinant human HOMER protein expressed in E. coli. [Swiss-Prot# Q86YM7]

Reactivity Notes

Immunogen sequence has 99% identity to rat, 98% to bovine, 96% to Xenopus and 74% to zebrafish.

Localization

Cytoplasm By similarity. Cell junction synapse postsynaptic cell membrane postsynaptic density. Cell junction synapse. Note: Postsynaptic density of neuronal cells. Isoform 1 inhibits surface expression of GRM5 causing it to be retained in the end

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for HOMER1 Antibody

Western Blot: HOMER1 Antibody [NBP1-44999]

Western Blot: HOMER1 Antibody [NBP1-44999]

Western Blot: HOMER1 Antibody [NBP1-44999] - Analysis of HOMER1 on human brain lysate.
Immunocytochemistry/ Immunofluorescence: HOMER1 Antibody [NBP1-44999]

Immunocytochemistry/ Immunofluorescence: HOMER1 Antibody [NBP1-44999]

Immunocytochemistry/Immunofluorescence: HOMER1 Antibody [NBP1-44999] - Detection of HOMER1 (Green) in Hela cells using NBP1-44999. Nuclei (Blue) are counterstained using Hoechst 33258.
Western Blot: HOMER1 Antibody [NBP1-44999]

Western Blot: HOMER1 Antibody [NBP1-44999]

Western Blot: HOMER1 Antibody [NBP1-44999] - Analysis of HOMER1 on mouse brain lysate.

Applications for HOMER1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Western Blot

1:1000
Application Notes
This HOMER1 antibody is useful in Immunocytochemistry/Immunofluorescence and Western blot, where a band at ~40 kDa is observed. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole antisera

Preservative

0.1% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HOMER1

Homer 1 (Homer protein homolog 1) belongs to the Homer family of proteins that regulate signal transduction through, and the trafficking of, glutamate receptors, as well as maintain and regulate extracellular glutamate levels in corticolimbic brain regions. The Homer 1 is enriched at excitatory synapses and binds group 1 metabotropic glutamate receptors (mGluRs).

Long Name

Homer Protein Homolog 1

Alternate Names

HOMER1A, HOMER1B, HOMER1C, SYN47, Ves-1

Entrez Gene IDs

9456 (Human); 26556 (Mouse)

Gene Symbol

HOMER1

UniProt

Q86YM7, Q9Z2Y3 (Mouse)

Additional HOMER1 Products

Product Documents for HOMER1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HOMER1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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