HRD1 Antibody (4H4)

Novus Biologicals, part of Bio-Techne | Catalog # H00084447-M01

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
H00084447-M01
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 4H4

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HRD1 Antibodies »

Product Specifications

Immunogen

SYVN1 (NP_079434, 238 a.a. ~ 318 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. HTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRS

Specificity

Reacts with synovial apoptosis inhibitor 1, synoviolin.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for HRD1 Antibody (4H4)

Western Blot: HRD1 Antibody (4H4) [H00084447-M01]

Western Blot: HRD1 Antibody (4H4) [H00084447-M01]

Western Blot: HRD1 Antibody (4H4) [H00084447-M01] - Analysis of SYVN1 expression in transfected 293T cell line by SYVN1 monoclonal antibody (M01), clone 4H4.Lane 1: SYVN1 transfected lysate(67.685 KDa).Lane 2: Non-transfected lysate.
ELISA: HRD1 Antibody (4H4) [H00084447-M01]

ELISA: HRD1 Antibody (4H4) [H00084447-M01]

ELISA: HRD1 Antibody (4H4) [H00084447-M01] - Detection limit for recombinant GST tagged SYVN1 is 0.1 ng/ml as a capture antibody.

Applications for HRD1 Antibody (4H4)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against recombinant protein in western blot and ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: HRD1

This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq]

Alternate Names

E3 ubiquitin-protein ligase synoviolin, EC 6.3.2, HRD1EC 6.3.2.-, KIAA1810Synovial apoptosis inhibitor 1, MGC40372, synovial apoptosis inhibitor 1, synoviolin

Entrez Gene IDs

84447 (Human)

Gene Symbol

SYVN1

UniProt

NP_115807 (Human)

Additional HRD1 Products

Product Documents for HRD1 Antibody (4H4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HRD1 Antibody (4H4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.