HtrA3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87211

Novus Biologicals, part of Bio-Techne
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NBP1-87211
NBP1-87211-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HTRA3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ITRFLTEFQDKQIKDWKKRFIGIRMRTITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEAVLTESPLLLEVRRGNDDLLFSIAP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HtrA3 Antibody

Immunohistochemistry-Paraffin: HtrA3 Antibody [NBP1-87211]

Immunohistochemistry-Paraffin: HtrA3 Antibody [NBP1-87211]

Immunohistochemistry-Paraffin: HtrA3 Antibody [NBP1-87211] - Staining of human testis shows moderate cytoplasmic positivity in Leydig cells.
Immunohistochemistry-Paraffin: HtrA3 Antibody [NBP1-87211]

Immunohistochemistry-Paraffin: HtrA3 Antibody [NBP1-87211]

Immunohistochemistry-Paraffin: HtrA3 Antibody [NBP1-87211] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: HtrA3 Antibody [NBP1-87211]

Immunohistochemistry-Paraffin: HtrA3 Antibody [NBP1-87211]

Immunohistochemistry-Paraffin: HtrA3 Antibody [NBP1-87211] - Staining of human placenta shows strong positivity in plasma.
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Applications for HtrA3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HTRA3

HtrA3 belongs to the human high-temperature requirement factor A (HtrA) family. HtrA3 has two isoforms (long and short), which are produced by alternative splicing. Similar to HtrA1, HtrA3 binds to various TGF-beta proteins and inhibits the signaling of BMP-4, -2 and TGF-beta 1. HtrA3 does not inhibit signaling originated from a constitutively active BMP receptor, indicating that the inhibition occurs upstream of the cell surface receptor.

Long Name

HtrA serine peptidase 3

Alternate Names

HTRA 3

Gene Symbol

HTRA3

Additional HTRA3 Products

Product Documents for HtrA3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HtrA3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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