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Human ATG4B Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB5279

R&D Systems, part of Bio-Techne
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MAB5279
MAB5279-SP

Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 515803

Product Specifications

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human ATG4B/Apg4b
Asp2-Leu393 (predicted)
Accession # Q9Y4P1

Specificity

Detects human ATG4B/Apg4b in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human ATG4A is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human ATG4B Antibody

Application
Recommended Usage

Immunoprecipitation

25 µg/mL
Sample: Cell lysates spiked with Recombinant Human ATG4B, see our available Western blot detection antibodies

Western Blot

1 µg/mL
Sample: Recombinant Human ATG4B

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: ATG4B

Autophagy related protein 4 homolog B (ATG4B), also known as autophagin 1 and Apg4b, is a cytosolic cysteine protease that is involved in autophagy, a biological process in which endogenous protein and damaged organelles are destroyed. Human ATG4B shares 98% and 95% amino acid sequence identity with chimpanzee and mouse ATG4B, respectively.

Long Name

ATG4 Autophagy Related 4 Homolog B

Alternate Names

Apg4B, AUTL1

Entrez Gene IDs

23192 (Human); 66615 (Mouse); 316640 (Rat)

Gene Symbol

ATG4B

UniProt

Additional ATG4B Products

Product Documents for Human ATG4B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human ATG4B Antibody

For research use only

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