Human Bcl-2 aa 41-54 Antibody

Bio-Techne includes R&D Systems | Catalog # 2291-MC

Discontinued Product
2291-MC has been discontinued. View all Bcl-2 products.

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunoprecipitation, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # YTH-8C8

View all Bcl-2 Antibodies »

Product Summary for Human Bcl-2 aa 41-54 Antibody

Immunogen

Human Bcl-2
aa 41-54

Specificity

Anti-Bcl-2 (Clone YTH-8C8) reacts with human Bcl-2.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human Bcl-2 aa 41-54 Antibody

Application
Recommended Usage

Immunoprecipitation

Western Blot

1:1000 dilution
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

This antibody is provided as purified immunoglobulin from mouse ascites in 1X PBS containing 0.01% sodium azide and 50% glycerol.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 °C.

Background: Bcl-2

The Bcl-2 family of proteins plays a crucial role in the regulation of cell death in many eukaryotic systems. The Bcl-2 gene was initially isolated from the t(14;18) chromosomal translocation found in human B-cell follicular lymphomas and was subsequently shown to repress cell death triggered by a diverse array of stimuli. However, the biochemical process by which Bcl-2 regulates cell death is poorly understood.

References

  1. Suzuki, M. et al. 2000, Cell 103:645-54.
  2. Hsu, Y.-T. et al. 1997, Proc. Natl. Acad. Sci. USA 94:3668-3672.
  3. Hsu, Y.-T. and R.J. Youle. 1997, J. Biol. Chem. 272:13829-13834.
  4. Neuchushtan, A. et al. 1999, EMBO J. 18:2330-2341.

Long Name

B Cell Lymphoma/Leukemia 2

Alternate Names

Bcl2

Entrez Gene IDs

596 (Human); 12043 (Mouse); 24224 (Rat)

Gene Symbol

BCL2

Additional Bcl-2 Products

Product Documents for Human Bcl-2 aa 41-54 Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human Bcl-2 aa 41-54 Antibody

For research use only

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