Human Carboxypeptidase B2/CPB2 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB6036
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Immunogen
Phe23-Val423 (predicted)
Accession # Q96IY4
Specificity
Clonality
Host
Isotype
Scientific Data Images for Human Carboxypeptidase B2/CPB2 Antibody
Detection of Human Carboxypeptidase B2/CPB2 by Western Blot.
Western blot shows lysates of human liver tissue. PVDF Membrane was probed with 2 µg/mL of Human Carboxypeptidase B2/CPB2 Monoclonal Antibody (Catalog # MAB6036) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). Specific bands were detected for Carboxypeptidase B2/CPB2 at approximately 45 and 50 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.Applications for Human Carboxypeptidase B2/CPB2 Antibody
Immunoprecipitation
Sample: Conditioned cell culture medium spiked with Recombinant Human Carboxypeptidase B2/CPB2, see our available Western blot detection antibodies.
Western Blot
Sample: Human liver tissue under non-reducing conditions only
Formulation, Preparation, and Storage
Purification
Reconstitution
Formulation
Shipping
Stability & Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Carboxypeptidase B2/CPB2
CPB2 (Carboxypeptidase B2; also CPU and TAFI) is a secreted, 50-60 kDa glycoprotein member of the peptidase M14 family of enzymes. It is expressed by hepatocytes (60 kDa) and platelets (50 kDa), with MW differences attributable to glycosylation. CPB2 is cleaved by thrombin and plasmin, generating a 36 kDa, relatively insoluble nonglycosylated enzymatically active fragment (TAFIa). Active CPB2 removes C-terminal
Alternate Names
Gene Symbol
UniProt
Additional Carboxypeptidase B2/CPB2 Products
Product Documents for Human Carboxypeptidase B2/CPB2 Antibody
Product Specific Notices for Human Carboxypeptidase B2/CPB2 Antibody
For research use only