Human CD20 F(ab')2 (Research Grade Ibritumomab Biosimilar) Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB11054-FAB2
Recombinant Monoclonal Antibody For Research Use Only
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Human IgG1 Clone # Hu10F2
Product Specifications
Immunogen
Human MS4A1/CD20
Specificity
Detects human CD20 in direct ELISAs.
Clonality
Monoclonal
Host
Human
Isotype
IgG1
Scientific Data Images for Human CD20 F(ab')2 (Research Grade Ibritumomab Biosimilar) Antibody
Detection of CD20 (Ibritumomab) in Human PBMCs by Flow Cytometry.
Human PBMCs were stained with (A) Human Anti-Human CD20 (Research Grade Ibritumomab Biosimilar) Monoclonal Antibody (Catalog # MAB11054-FAB2) or (B) unstained, followed by followed by APC-conjugated Anti-Human IgG Secondary Antibody (F0135) and Mouse anti-Human CD19 PE-conjugated Monoclonal Antibody (FAB4867P). View our protocol for Staining Membrane-associated Proteins.Applications for Human CD20 F(ab')2 (Research Grade Ibritumomab Biosimilar) Antibody
Application
Recommended Usage
Flow Cytometry
0.25 µg/106 cells
Sample: Human PBMC
Sample: Human PBMC
Formulation, Preparation, and Storage
Purification
Protein A or G purified from cell culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CD20
CD20 is a 297 amino acid (aa) non-glycosylated type III membrane protein that is the founding member of the MS4A tetraspanin protein family. It is expressed on pre-B, naïve and mature B lymphocytes and B-cell lymphomas. CD20 is associated with lipid rafts upon crosslinking, and appears to play a role in regulation of ion influx. The one extracellular segment of 48 aa shows 65% aa sequence identity between human and mouse CD20.
Long Name
Cluster of Differentiation 20
Alternate Names
B1, Bp35, CD20, LEU-16, Ly-44, MS4A1, S7
Entrez Gene IDs
Gene Symbol
MS4A1
Additional CD20 Products
Product Specific Notices for Human CD20 F(ab')2 (Research Grade Ibritumomab Biosimilar) Antibody
For research use only
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