Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD5 Biotinylated Monoclonal Antibody (Catalog # FAB1636B, filled histogram) or isotype control antibody (Catalog # IC003B, open histogram), followed by Streptavidin-Phycoerythrin (Catalog # F0040). View our protocol for Staining Membrane-associated Proteins.

Applications for Human CD5 Biotinylated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: Human peripheral blood lymphocytes

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD5

CD5, also known as Leu-1, is a type I transmembrane protein belonging to the scavenger receptor cysteine-rich (SRCR) superfamily. It is expressed on thymocytes, T cells and the B1a subpopulation of B cells. CD5 binds the C-type lectin, CD72, and modulates signaling through the antigen receptors on T and B cells. CD5 has been shown to provide either positive or negative co-stimulatory signals depending on cell type to regulate immune responses.

References

Ledbetter, J.A. et al. (1985) J. Immunol. 135:2331.
Damle, N.K. et al. (1988) J. Immunol. 140:1753.

Alternate Names

CD5

Entrez Gene IDs

921 (Human); 12507 (Mouse)

Gene Symbol

CD5

UniProt

P06127

Additional CD5 Products

Product Documents for Human CD5 Biotinylated Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human CD5 Biotinylated Antibody

For research use only

Citations
Reviews

Human CD5 Biotinylated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB1636B

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all CD5 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human CD5 Biotinylated Antibody

Detection of CD5 in Human Blood Lymphocytes by Flow Cytometry.