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Human CD7 Biotinylated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB7579B

R&D Systems, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Biotin

Antibody Source

Monoclonal Mouse IgG2B Clone # 848438

Product Specifications

Immunogen

Human embryonic kidney cell line HEK293-derived human CD7
Ala26-Pro180
Accession # P09564

Specificity

Detects human CD7 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse CD7 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Human CD7 Biotinylated Antibody

Detection of CD7 in Human PBMC lymphocytes by Flow Cytometry.

Human CD19- PBMC lymphocytes were stained with Mouse Anti-Human CD3e APC-conjugated Monoclonal Antibody (FAB100A) and either (A) Mouse Anti-Human CD7 Biotinylated Monoclonal Antibody (Catalog # FAB7579B) or (B) Mouse IgG2B Isotype Control (IC0041B) followed by Phycoerythrin-conjugated Streptavidin (F0040). Staining was performed using our Staining Membrane Proteins protocol.

Applications for Human CD7 Biotinylated Antibody

Application
Recommended Usage

Flow Cytometry

0.25 µg/106 cells
Sample: Human PBMC lymphocytes
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitution default not known

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD7

CD7, also known as gp40, is a 40 kD type I transmembrane glycoprotein member of the immunoglobulin superfamily. It is found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion.

Alternate Names

CD7, LEU-9, TP41

Entrez Gene IDs

924 (Human); 12516 (Mouse); 303747 (Rat); 102124399 (Cynomolgus Monkey)

Gene Symbol

CD7

UniProt

Additional CD7 Products

Product Documents for Human CD7 Biotinylated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human CD7 Biotinylated Antibody

For research use only

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