Human CLEC3B/Tetranectin Antibody
R&D Systems, part of Bio-Techne | Catalog # AF5170
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Sheep IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CLEC3B/Tetranectin
Glu22-Val202
Accession # P05452
Glu22-Val202
Accession # P05452
Specificity
Detects human CLEC3B/Tetranectin in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human (rh) CLEC1, rhCLEC2, rhCLEC10A, and rhCLEC14A is observed.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for Human CLEC3B/Tetranectin Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Human CLEC3B/Tetranectin
Sample: Recombinant Human CLEC3B/Tetranectin
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CLEC3B/Tetranectin
CLEC3B (C-type lectin domain family 3-member B; also Tetranectin) is a 20 kDa, secreted member of the C type lectin superfamily. It is produced by multiple cell types, including monocytes, neutrophils, fibroblasts, hepatocytes and various endocrine cells. Although named Tetranectin, CLEC3B is actually a nondisulfide linked homotrimer. It binds to plasminogen, sulfated polysaccharides, and fibrin. Human CLEC3B precursor is 202 amino acids (aa) in length. It contains a signal sequence (aa 1-21), a coiled coil region that mediates trimerization (aa 26-52) and a C type lectin domain (aa 77-198). CLEC3B contains O-linked glycosylation. Mature human CLEC3B is 81% aa identical to mouse CLEC3B.
Long Name
C-type Lectin-like Receptor 3B
Alternate Names
TETN, Tetranectin, TNA
Gene Symbol
CLEC3B
UniProt
Additional CLEC3B/Tetranectin Products
Product Documents for Human CLEC3B/Tetranectin Antibody
Product Specific Notices for Human CLEC3B/Tetranectin Antibody
For research use only
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