Human Coagulation Factor XIV/Protein C Antibody
R&D Systems, part of Bio-Techne | Catalog # AF3349
Key Product Details
Species Reactivity
Human
Applications
Immunoprecipitation, Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Coagulation Factor XIV/Protein C
Ala43-Pro461
Accession # P04070
Ala43-Pro461
Accession # P04070
Specificity
Detects human Coagulation Factor XIV/Protein C in direct ELISAs and Western blots.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Human Coagulation Factor XIV/Protein C Antibody
Application
Recommended Usage
Immunoprecipitation
25 µg/mL
Sample: Conditioned cell culture medium spiked with Recombinant Human Coagulation Factor XIV/Protein C (Catalog # 3349-SE), see our available Western blot detection antibodies
Sample: Conditioned cell culture medium spiked with Recombinant Human Coagulation Factor XIV/Protein C (Catalog # 3349-SE), see our available Western blot detection antibodies
Western Blot
0.1 µg/mL
Sample: Recombinant Human Coagulation Factor XIV/Protein C (Catalog # 3349-SE)
Sample: Recombinant Human Coagulation Factor XIV/Protein C (Catalog # 3349-SE)
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Reviewed Applications
Read 1 review rated 4 using AF3349 in the following applications:
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Coagulation Factor XIV/Protein C
Coagulation factor XIV, also known as Protein C, has anti-coagulation activity by degrading factors VIIIa and Va, which are required for thrombin activation. Protein C deficiency results in hereditary thrombophilia, and a severe recessive form may result in massive thrombosis fatal to patient. The deduced amino acid sequence of human protein C predicts a signal peptide (aa 1‑32), a propeptide (aa 33‑42), and a mature chain (aa 43‑461), which can be converted into two disulfide-linked chains (light: aa 43‑199 and heavy: aa 200‑461). The amino acid sequence of human protein C is 99.8%, 80%, 70%, 69% and 54% identical to that of chimpanzee, canine, rat, mouse and chicken.
Long Name
Vitamin K-dependent Protein C
Alternate Names
Autoprothrombin IIA, PROC, Protein C
Gene Symbol
PROC
UniProt
Additional Coagulation Factor XIV/Protein C Products
Product Documents for Human Coagulation Factor XIV/Protein C Antibody
Product Specific Notices for Human Coagulation Factor XIV/Protein C Antibody
For research use only
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