Human CXCR4 Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB170B
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry, Immunocytochemistry
Label
Biotin
Antibody Source
Monoclonal Mouse IgG2A Clone # 12G5
Product Specifications
Immunogen
CP-MAC-infected SUP-T1 human T cell lymphoblastic lymphoma line
Accession # P61073
Accession # P61073
Specificity
Detects human CXCR4.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Human CXCR4 Biotinylated Antibody
Detection of CXCR4 in Human Blood Lymphocytes by Flow Cytometry.
Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR4 Biotinylated Monoclonal Antibody (Catalog # FAB170B) followed by Streptavidin-Phycoerythrin (Catalog # F0040) and Mouse Anti-Human CD19 APC-conjugated Monoclonal Antibody (Catalog # FAB4867A). View our protocol for Staining Membrane-associated Proteins.
Detection of CXCR4 in Jurkat vs K562 cells by Flow Cytometry
Jurkat (filled histogram) vs K562 (open histogram) cells were stained with Mouse Anti-Human CXCR4 Biotinylated Monoclonal Antibody (Catalog # FAB170B). View our protocol for Staining Membrane-associated Proteins.Applications for Human CXCR4 Biotinylated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: see below
Sample: see below
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from ascites
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CXCR4
CXCR4, also known as CD184, is a G-protein-linked seven transmembrane spanning receptor that binds stromal cell-derived factor-1 (SDF-1). CXCR4 acts as a co-factor for T-cell tropic HIV-1 and -2 viral entry into cells.
References
- Endres, M.J. et al. (1996) Cell 87:745.
Long Name
C-X-C Motif Chemokine Receptor 4
Alternate Names
CD184, D2S201E, FB22, Fusin, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYRL, NPYY3R, WHIMS
Gene Symbol
CXCR4
UniProt
Additional CXCR4 Products
Product Documents for Human CXCR4 Biotinylated Antibody
Product Specific Notices for Human CXCR4 Biotinylated Antibody
For research use only
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