Human CXCR6 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB6991
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
CyTOF-ready, Flow Cytometry
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2A Clone # 1010910
Product Specifications
Immunogen
HEK293 human embryonic kidney cell line transfected with human CXCR6
Met1-Leu342
Accession # O00574
Met1-Leu342
Accession # O00574
Specificity
Detects human CXCR6 in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Human CXCR6 Antibody
Detection of CXCR6 in Human PBMCs Stimulated to Induce Th1 Cells by Flow Cytometry.
Human CD3+peripheral blood mononuclear cells (PBMCs) cultured with plate bound anti-Human CD3 and CD28 Antibodies, Anti-Human IL-4 Polyclonal Antibody (Catalog # AB-204-NA; 20 µg/mL) and 10 ng/mL Recombinant Human IL-12 (Catalog # 219-IL) for 5 days to induce Th1 cell development were stained with (A) Mouse Anti-Human CXCR6 Monoclonal Antibody (Catalog # MAB6991) or (B) Isotype control antibody (Catalog # MAB003) followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B) and Mouse Anti-Human CD4 APC-conjugated Monoclonal Antibody (Catalog # FAB3791A). View our protocol for Staining Membrane-associated Proteins.Applications for Human CXCR6 Antibody
Application
Recommended Usage
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
Flow Cytometry
0.25 µg/106 cells
Sample: Human PBMCs Stimulated to Induce Th1 Cells
Sample: Human PBMCs Stimulated to Induce Th1 Cells
Formulation, Preparation, and Storage
Purification
Protein A or G purified from ascites
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CXCR6
CXCR6, also known as BONZO, STRL33, TYMSTR, is the receptor for the C-X-C chemokine CXCL16. CXCR6 is a G protein coupled protein receptor (GPCR) expressed on activated T cells and tumor-infiltrating lymphocytes, and it has been identified as an entry co-receptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4.
Alternate Names
Bonzo, CD186, CXCR6, STRL33
Gene Symbol
CXCR6
UniProt
Additional CXCR6 Products
Product Documents for Human CXCR6 Antibody
Product Specific Notices for Human CXCR6 Antibody
For research use only
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