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Human Desmin Biotinylated Antibody

R&D Systems, part of Bio-Techne | Catalog # BAF3844

R&D Systems, part of Bio-Techne
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BAF3844

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG

Product Specifications

Immunogen

E. coli-derived recombinant human Desmin
Val261-Leu470
Accession # P17661

Specificity

Detects human Desmin in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Desmin Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human Desmin
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Desmin

Desmin is a 53 kDa, muscle-specific molecule that belongs to the intermediate filament superfamily of cytoskeletal proteins. Cytoplasmic Desmin homopolymers form stable filamentous networks that stabilize lateral alignments of myofibrils. Human Desmin is 470 amino acid peptide. It contains an N-terminal head segment (aa 1‑84), multiple coiled regions (aa 109‑412) and a tail region (aa 413‑470). Single amino acid substitutions and three-amino acid deletions are associated with cardio‑skeletal myopathies. Most mutations affect filament assembly. Desmin is a highly conserved protein. Over the region used as immunogen, human Desmin is 99% identical to the corresponding mouse, canine and porcine protein sequences.

Alternate Names

CMD1I, DES

Entrez Gene IDs

1674 (Human); 13346 (Mouse); 64362 (Rat)

Gene Symbol

DES

UniProt

Additional Desmin Products

Product Documents for Human Desmin Biotinylated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Desmin Biotinylated Antibody

For research use only

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