Human Exostosin-like 3/EXTL3 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB2635

R&D Systems, part of Bio-Techne
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MAB2635
MAB2635-SP
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Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 311007

View all Exostosin-like 3/EXTL3 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Exostosin-like 3/EXTL3
Thr52-Ile919
Accession # O43909

Specificity

Detects human Exostosin-like 3/EXTL3 in direct ELISAs and Western blots.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Human Exostosin-like 3/EXTL3 Antibody

Application
Recommended Usage

Immunoprecipitation

25 µg/mL
Sample: Conditioned cell culture medium spiked with Recombinant Human Exostosin-like 3/EXTL3, see our available Western blot detection antibodies

Western Blot

1 µg/mL
Sample: Recombinant Human Exostosin-like 3/EXTL3

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Exostosin-like 3/EXTL3

EXTL3 is an ER-resident type II transmembrane protein belonging to the EXT family of tumor suppressor genes. EXT family members are glycosyl transferases that are involved in the synthesis of the glycosaminoglycan chains of heparan sulfate proteoglycans. EXTL3 was also reported to be a receptor for the REG protein, a pancreatic beta-cell regeneration factor. The amino acid sequence of rhEXTL3 is 98%, 97%, 88%, and 83% identical to that of dog, rat/mouse, Xenopus and zebrafish.

Alternate Names

Exostosin like 3, EXTL3

Entrez Gene IDs

2137 (Human)

Gene Symbol

EXTL3

UniProt

O43909

Additional Exostosin-like 3/EXTL3 Products

Product Documents for Human Exostosin-like 3/EXTL3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human Exostosin-like 3/EXTL3 Antibody

For research use only

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