Human Exostosin-like 3/EXTL3 Lumenal Domain Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF2635
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Biotin
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Exostosin-like 3/EXTL3 Lumenal Domain
Thr52-Ile919
Accession # O43909
Thr52-Ile919
Accession # O43909
Specificity
Detects human Exostosin-like 3/EXTL3 lumenal domain in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human EXTL1 is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Human Exostosin-like 3/EXTL3 Lumenal Domain
Sample: Recombinant Human Exostosin-like 3/EXTL3 Lumenal Domain
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Exostosin-like 3/EXTL3
Exostosin-like 3 (EXTL3) is an ER-resident type II transmembrane protein belonging to the EXT family of tumor suppressor genes. EXT family members are glycosyl transferases that are involved in the synthesis of the glycosaminoglycan chains of heparan sulfate proteoglycans. EXTL3 was also reported to be a receptor for the REG protein, a pancreatic beta-cell regeneration factor. The lumenal domains of human, mouse and rat share 97% amino acid sequence identity.
Additional Exostosin-like 3/EXTL3 Products
Product Specific Notices
For research use only
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